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Book Publication

Bio-chemical Process Monitoring with Terahertz Sensors

Host Publication: THz for CBRN and Explosives' Detection and Diagnosis 2017

Authors: Y. Zhang, V. Matvejev, S. Declerck, S. Stroobants, G. Pandey, G. He, D. Mangelings, D. Maes, S. Muyldermans and J. Stiens

Edition: 1

Publisher: Springer

Publication Year: 2017

Number of Pages: 7

ISBN: 978-94-024-1092-1, 978-94-024-1095-2


Abstract:

An in-house developed Label-free Immobilization-free Terahertz(THz) sensor has shown its potential in various applications. In this paper, we present the exper-imental results in the field of High Performance Liquid Chromatography(HPLC) and protein crystallization. Ultra-violet(UV) detectors are very commonly used as a detection technique in HPLC systems. However, it relies on labelling when target substances do not absorb UV light. Therefore it has the drawback of increased cost and time consumption. Our experimental result shows that THz sensor has the potential to replace UV sensor integrated on the HPLC machine as it is able to detect both UV and non-UV absorbing substances without labelling. Meanwhile, the THz sensor is also deployed for the first time to follow protein crystallization process.

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+32 (0)02 629 239

ghe@etrovub.be

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Prof. Dr. Ir. Johan Stiens

+32 (0)02 629 239

jstiens@etrovub.be

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