Leon Verbruggen, N. Dumarey, Hilde Van De Velde, V. Rebmann, J. Flament, C. Van Waeyenberge, H. Grosse-Wilde, Christian Demanet
We investigated correlations between soluble HLA-DR (sHLA-DR) molecules and several clinical, biological and genetic parameters associated with rheumatoid arthritis (RA) disease activity. Serum sHLA-DR concentrations were determined in 146 samples from 89 RA patients by an ELISA format, using an antibody combination of mouse and rat monoclonal anti-human HLA-DR antibodies. The mean sHLA-DR serum level in RA patients was significantly increased with 277±19 ng/ml compared to 142±13 ng/ml of 80 healthy controls (P
Verbruggen, L, Dumarey, N, Van De Velde, H, Rebmann, V, Flament, J, Van Waeyenberge, C, Grosse-Wilde, H & Demanet, C 2000, 'Soluble HLA-DR antigen levels in serum correlate with rheumatoid arthritis disease activity and the presence of disease-associated epitopes.', Tissue Antigens, vol. 56, pp. 436-440.
Verbruggen, L., Dumarey, N., Van De Velde, H., Rebmann, V., Flament, J., Van Waeyenberge, C., Grosse-Wilde, H., & Demanet, C. (2000). Soluble HLA-DR antigen levels in serum correlate with rheumatoid arthritis disease activity and the presence of disease-associated epitopes. Tissue Antigens, 56, 436-440.
@article{3d846f4aef7a4235b054a807bbf10e83,
title = "Soluble HLA-DR antigen levels in serum correlate with rheumatoid arthritis disease activity and the presence of disease-associated epitopes.",
abstract = "We investigated correlations between soluble HLA-DR (sHLA-DR) molecules and several clinical, biological and genetic parameters associated with rheumatoid arthritis (RA) disease activity. Serum sHLA-DR concentrations were determined in 146 samples from 89 RA patients by an ELISA format, using an antibody combination of mouse and rat monoclonal anti-human HLA-DR antibodies. The mean sHLA-DR serum level in RA patients was significantly increased with 277±19 ng/ml compared to 142±13 ng/ml of 80 healthy controls (P",
keywords = "soluble HLA-DR, major histocompatibility complex, HLA-DRB1, rheumatoid arthritis",
author = "Leon Verbruggen and N. Dumarey and {Van De Velde}, Hilde and V. Rebmann and J. Flament and {Van Waeyenberge}, C. and H. Grosse-Wilde and Christian Demanet",
year = "2000",
language = "English",
volume = "56",
pages = "436--440",
journal = "Tissue Antigens",
issn = "0001-2815",
publisher = "John Wiley and Sons Ltd",
}