Boonen, P., Buls, N., Vandemeulebroucke, J., Van Gompel, G., Aerden, D., & De Mey, J. (2018). Quantification of blood velocity from time-resolved CT angiography on a 256-slice CT. In L. Marti-Bonmati (Ed.), ECR 2018 - BOOK OF ABSTRACTS (pp. 406-406). (Insights into Imaging). Springer Berlin. https://doi.org/10.1007/s13244-018-0603-8

@inbook{ab999e570ef7404fa4f0208bf2aebd52,
title = "Quantification of blood velocity from time-resolved CT angiography on a 256-slice CT",
abstract = "Purpose: To quantify the blood velocity in the arteries of the lower extremitiesand to investigate the correlation with peripheral arterial disease (PAD).Methods and Materials: 7 Patients with suspicion of PAD underwent timeresolvedComputed Tomography Angiography (CTA) in addition to theirstandard run-off CTA, consisting of 18 repeated axial acquisitions at 2sinterphase delay at the level of the calves with 16cm collimation (RevolutionCT, GE Healthcare). Image data was processed using in-house developedprocessing tools. Motion during the acquisitions was compensated by applyingregistration, after which the anterior tibial artery, posterior tibial artery andperoneal artery were automatically segmented by identifying large intensitychanges over time. Subsequently, blood velocity was quantified in the arteriesby creating time attenuation curves (TAC) of the arterial cross-sections in everyslice and determining the time to peak (TTP).Results: The described method led to plausible velocity estimations in allarteries (n=18) for patients that were considered healthy (n=3). Forpathological patients (n=4), only 12 out of 22 arteries could be quantified due tosuboptimal bolus arrival, severe calcification or occlusions. For arteries ofhealthy patients, blood velocity was normally distributed (p=0.282) with amedian value of 82.3 mm/s (95% CI= 55.5- 89.9 mm/s). Blood velocity inarteries of pathological patients was observed to be significantly lower, 30.7mm/s (95% CI= 27.4-45.7 mm/s), p<0.01.Conclusion: Time-resolved CT data allows to quantify blood velocity in thearteries of the lower extremities. In heavily occluded arteries, the contrast wasinsufficient in order to quantify velocity.",
keywords = "Vascular, CT Angiography, PERIPHERAL ARTERIAL-DISEASE, dynamic contrast enhanced CT, Leg, Velocity, Calcification",
author = "Pieter Boonen and Nico Buls and Jef Vandemeulebroucke and {Van Gompel}, Gert and Dimitri Aerden and {De Mey}, Johan",
year = "2018",
month = feb,
day = "15",
doi = "10.1007/s13244-018-0603-8",
language = "English",
series = "Insights into Imaging",
publisher = "Springer Berlin",
pages = "406--406",
editor = "Luis Marti-Bonmati",
booktitle = "ECR 2018 - BOOK OF ABSTRACTS",
address = "Germany",
note = "European Congres of Radiology (ECR 2018) ; Conference date: 28-02-2018 Through 04-03-2018",
}