Proof-of-concept of a hybrid integrated ultra-sensitive high-Q resonator structure, has been demonstrated in the past. It is a remarkable feature that such high Q-factor can be obtained in the presence of highly absorbing liquids such as water. Mechanical stability measurements of this proof-of-concept solution show an extreme low frequency (<100ppm) and amplitude (<40ppm) drift after 6 hours. In this paper we also report on the progress towards a first fully integrated solution compatible with micro-fluidics and HPLC systems and discuss on various applications in life sciences: biomolecule concentration measurements, monitoring biochemical reactions or the denaturation of biomolecules.
Stiens, J, Matvejev, V, Zhang, Y & De Tandt, C 2013, Immobilization- and label-free sensing of biomolecules solvated in nanoliter liquids at (sub)- THz wave frequencies with resonating sensor structures featuring loaded Q-factors above 10^4. in EUROPEAN MICROWAVE WEEK 2013. EUROPEAN MICROWAVE WEEK 2013, IEEE, USA, Unknown, 11/10/13.
Stiens, J., Matvejev, V., Zhang, Y., & De Tandt, C. (2013). Immobilization- and label-free sensing of biomolecules solvated in nanoliter liquids at (sub)- THz wave frequencies with resonating sensor structures featuring loaded Q-factors above 10^4. In EUROPEAN MICROWAVE WEEK 2013 (EUROPEAN MICROWAVE WEEK 2013). IEEE.
@inbook{8bec4005cdee4242b38fd7dfb74aa58e,
title = "Immobilization- and label-free sensing of biomolecules solvated in nanoliter liquids at (sub)- THz wave frequencies with resonating sensor structures featuring loaded Q-factors above 10^4",
abstract = "Proof-of-concept of a hybrid integrated ultra-sensitive high-Q resonator structure, has been demonstrated in the past. It is a remarkable feature that such high Q-factor can be obtained in the presence of highly absorbing liquids such as water. Mechanical stability measurements of this proof-of-concept solution show an extreme low frequency (<100ppm) and amplitude (<40ppm) drift after 6 hours. In this paper we also report on the progress towards a first fully integrated solution compatible with micro-fluidics and HPLC systems and discuss on various applications in life sciences: biomolecule concentration measurements, monitoring biochemical reactions or the denaturation of biomolecules.",
keywords = "Terahertz, Sensor, Biomolecules",
author = "Johan Stiens and Vladimir Matvejev and Yuchen Zhang and {De Tandt}, Cathleen",
year = "2013",
month = oct,
day = "11",
language = "English",
series = "EUROPEAN MICROWAVE WEEK 2013",
publisher = "IEEE",
booktitle = "EUROPEAN MICROWAVE WEEK 2013",
note = "Unknown ; Conference date: 11-10-2013",
}