Gasser, A., Lapauw, T., Ingelberts, H., Hoving, W., & Kuijk, M. (2020). Compact time-resolved fluorescence spectrometer. In P. Schelkens, & T. Kozacki (Eds.), Optics, Photonics and Digital Technologies for Imaging Applications VI (Vol. 11353). Article 1135319 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 11353). SPIE. https://doi.org/10.1117/12.2554164

@inproceedings{0e9a52c0145b422f85ebe6a08d01765f,
title = "Compact time-resolved fluorescence spectrometer",
abstract = "Fluorescence-lifetime spectroscopy is currently used in several applications for rapid medical diagnoses of diseases, e.g. cancer, oral carcinoma, actinic cheilitis and tissue diagnosis. In addition, it has various applications in biology, chemistry analysis, pharmaceutical applications and physics.Existing fluorescence spectrometer systems are bulky and large optical setups and using intricate monochromators with movable parts or use non-tunable bandpass filters. Therefore, the user has to adjust the filters when changing the fluorophore.In this work, we propose a spectrometer setup that can be tuned for different emission wavelengths using spatial light modulators (SLM) based on MEMS technology. A proof-of-concept spectrometer is built with a very compact optical layout following a Fastie-Ebert configuration followed by a digital micromirror device for wavelength selection along with a novel high-speed-gated single CAPS pixel detector. The setup operates in the spectral range between 510 and 645 nm. In this paper, two set of measurements are reported. Firstly, the selection of different wavelengths over the operation region. Secondly, the measurement of fluorescence lifetime of a sample at different wavelengths.",
keywords = "Fluorescence lifetime, Time Resolved Spectrometer, Digital Micromirror Device, Spatial Light Modulator, Time-gated CAPS single pixel",
author = "Anas Gasser and Thomas Lapauw and Hans Ingelberts and Willem Hoving and Maarten Kuijk",
note = "Funding Information: This work is done at the Electronics and Informatics department at the Vrije Universiteit Brussel (VUB) in Belgium and Anteryon B.V. in Eindhoven, Netherlands within the project xCLASS (2017-2021). xCLASS has received funding from the European Union{\textquoteright}s Horizon 2020 research and innovation programme under the Marie Sk{\l}odowska-Curie grant agreement No. 765635. In addition, it is funded in part by the Research Council of the Vrije Universiteit Brussel (SRP 19). Funding Information: This work is done at the Electronics and Informatics department at the Vrije Universiteit Brussel (VUB) in Belgium and Anteryon B.V. in Eindhoven, Netherlands within the project xCLASS (2017-2021). xCLASS has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 765635. In addition, it is funded in part by the Research Council of the Vrije Universiteit Brussel (SRP 19). Publisher Copyright: {\textcopyright} 2020 SPIE Copyright: Copyright 2020 Elsevier B.V., All rights reserved.; SPIE Photonics Europe, 2020 ; Conference date: 06-04-2020 Through 10-04-2020",
year = "2020",
month = apr,
day = "14",
doi = "10.1117/12.2554164",
language = "English",
isbn = "9781510634787",
volume = "11353",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Schelkens, { Peter } and Kozacki, {Tomasz }",
booktitle = "Optics, Photonics and Digital Technologies for Imaging Applications VI",
address = "United States",
url = "https://spie.org/conferences-and-exhibitions/photonics-europe?utm_id=repe20pae&spMailingID=4563957&spUserID=MjA2NDExNDgyMTA3S0&spJobID=920584314&spReportId=OTIwNTg0MzE0S0&SSO=1",
}