The aim of this study was to evaluate and present an automated method for registration of magnetic resonance imaging (MRI) and computed tomography (CT) or cone beam CT (CBCT) images of the mandibular region for patients with oral squamous cell carcinoma (OSCC). Registered MRI and (CB)CT could facilitate the three-dimensional virtual planning of surgical guides employed for resection and reconstruction in patients with OSCC with mandibular invasion. MRI and (CB)CT images were collected retrospectively from 19 patients. MRI images were aligned with (CB)CT images employing a rigid registration approach (stage 1), a rigid registration approach using a mandibular mask (stage 2), and two non-rigid registration approaches (stage 3). Registration accuracy was quantified by the mean target registration error (mTRE), calculated over a set of landmarks annotated by two observers. Stage 2 achieved the best registration result, with an mTRE of 2.5 ± 0.7 mm, which was comparable to the inter- and intra-observer variabilities of landmark placement in MRI. Stage 2 was significantly better aligned compared to all approaches in stage 3. In conclusion, this study demonstrated that rigid registration with the use of a mask is an appropriate image registration method for aligning MRI and (CB)CT images of the mandibular region in patients with OSCC.
Polfliet, M, Hendriks, MS, Guyader, J-M, ten Hove, I, Mast, H, Vandemeulebroucke, J, van der Lugt, A, Wolvius, EB & Klein, S 2021, 'Registration of magnetic resonance and computed tomography images in patients with oral squamous cell carcinoma for three-dimensional virtual planning of mandibular resection and reconstruction', International Journal of Oral and Maxillofacial Surgery, vol. 50, no. 10, pp. 1386-1393. https://doi.org/10.1016/j.ijom.2021.01.003
Polfliet, M., Hendriks, M. S., Guyader, J. .-M., ten Hove, I., Mast, H., Vandemeulebroucke, J., van der Lugt, A., Wolvius, E. B., & Klein, S. (2021). Registration of magnetic resonance and computed tomography images in patients with oral squamous cell carcinoma for three-dimensional virtual planning of mandibular resection and reconstruction. International Journal of Oral and Maxillofacial Surgery, 50(10), 1386-1393. https://doi.org/10.1016/j.ijom.2021.01.003
@article{de18b21b574f4a28b6ab1bbfc1a5b4c0,
title = "Registration of magnetic resonance and computed tomography images in patients with oral squamous cell carcinoma for three-dimensional virtual planning of mandibular resection and reconstruction",
abstract = "The aim of this study was to evaluate and present an automated method for registration of magnetic resonance imaging (MRI) and computed tomography (CT) or cone beam CT (CBCT) images of the mandibular region for patients with oral squamous cell carcinoma (OSCC). Registered MRI and (CB)CT could facilitate the three-dimensional virtual planning of surgical guides employed for resection and reconstruction in patients with OSCC with mandibular invasion. MRI and (CB)CT images were collected retrospectively from 19 patients. MRI images were aligned with (CB)CT images employing a rigid registration approach (stage 1), a rigid registration approach using a mandibular mask (stage 2), and two non-rigid registration approaches (stage 3). Registration accuracy was quantified by the mean target registration error (mTRE), calculated over a set of landmarks annotated by two observers. Stage 2 achieved the best registration result, with an mTRE of 2.5 ± 0.7 mm, which was comparable to the inter- and intra-observer variabilities of landmark placement in MRI. Stage 2 was significantly better aligned compared to all approaches in stage 3. In conclusion, this study demonstrated that rigid registration with the use of a mask is an appropriate image registration method for aligning MRI and (CB)CT images of the mandibular region in patients with OSCC.",
keywords = "oral squamous cell carcinoma, mandibular reconstruction, X-ray computed tomography, magnetic resonance imaging, multimodal imaging, medical image processing",
author = "M. Polfliet and Hendriks, {M. S.} and Guyader, {J. -M.} and {ten Hove}, I. and H. Mast and J. Vandemeulebroucke and {van der Lugt}, A. and Wolvius, {E. B.} and S. Klein",
note = "Funding Information: This study was partially funded by Fonds NutsOhra (nr. 1404-048 ). Publisher Copyright: {\textcopyright} 2021 The Author(s) Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = oct,
doi = "10.1016/j.ijom.2021.01.003",
language = "English",
volume = "50",
pages = "1386--1393",
journal = "International Journal of Oral and Maxillofacial Surgery",
issn = "0901-5027",
publisher = "Churchill Livingstone",
number = "10",
}