Although sound methods exist to derive physical perfusion parameters like regional blood volume, blood flow and permeability from dynamic contrast enhanced studies, we found that these methods require a higher temporal resolution than currently is practically achievable for volumetric CT with full nodule coverage. Yet, the elaborated average enhancement color overlays allow for easy, semi-quantitative evaluation of therapy response by radiologists. The methodology developed in this study provides hence a useful tool that can be used in clinical practice to evaluate tumour response as a viable alternative to the less prevalent PET imaging modality.
Clerinx, P, Deklerck, R, Nieboer, K, Bral, S, Verellen, D, Storme, G, De Mey, J & Nyssen, M (ed.) 2007, Pulmonary Nodule Radiotherapy Follow-up using Dynamic Contrast Enhancement CT. in Seventh Belgian Day on Biomedical Engineering.
Clerinx, P., Deklerck, R., Nieboer, K., Bral, S., Verellen, D., Storme, G., De Mey, J., & Nyssen, M. (Ed.) (2007). Pulmonary Nodule Radiotherapy Follow-up using Dynamic Contrast Enhancement CT. In Seventh Belgian Day on Biomedical Engineering
@inbook{c35b31f6266d48418b10fbde9e53fff7,
title = "Pulmonary Nodule Radiotherapy Follow-up using Dynamic Contrast Enhancement CT",
abstract = "Although sound methods exist to derive physical perfusion parameters like regional blood volume, blood flow and permeability from dynamic contrast enhanced studies, we found that these methods require a higher temporal resolution than currently is practically achievable for volumetric CT with full nodule coverage. Yet, the elaborated average enhancement color overlays allow for easy, semi-quantitative evaluation of therapy response by radiologists. The methodology developed in this study provides hence a useful tool that can be used in clinical practice to evaluate tumour response as a viable alternative to the less prevalent PET imaging modality.",
keywords = "radiotherapy, pulmonary, perfusion, lung, lung nodule, dynamic contrast enhanced CT, treatment outcome",
author = "Peter Clerinx and Rudi Deklerck and K Nieboer and S. Bral and Dirk Verellen and Guy Storme and {De Mey}, Johan and Marc Nyssen",
note = "Marc Nyssen",
year = "2007",
month = nov,
day = "30",
language = "English",
booktitle = "Seventh Belgian Day on Biomedical Engineering",
}