Publication Details
Overview
 
 
Sofie Tilborghs, Sofie Tilborghs, Ine Dirks, Ine Dirks, Lucas Fidon, Lucas Fidon, Siri Willems, Siri Willems, Tom Eelbode, Tom Eelbode, Jeroen Bertels, Jeroen Bertels, Bart Ilsen, Bart Ilsen, Arne Brys, Arne Brys, Adriana Dubbeldam, Adriana Dubbeldam, , , Panagiotis Gonidakis, Panagiotis Gonidakis, Sebastián Amador Sánchez, Sebastián Amador Sánchez, Annemiek Snoeckx, Annemiek Snoeckx, Paul M. Parizel, Paul M. Parizel, , , Dirk Vandermeulen, Dirk Vandermeulen, Tom Vercauteren, Tom Vercauteren, David Robben, David Robben, Dirk Smeets, Dirk Smeets, Frederik Maes, Frederik Maes, Jef Vandemeulebroucke, Jef Vandemeulebroucke, Paul Suetens, Paul Suetens
 

Working paper

Abstract 

Recent research on COVID-19 suggests that CT imaging provides useful information to assess disease progression and assist diagnosis, in addition to help understanding the disease. There is an increasing number of studies that propose to use deep learning to provide fast and accurate quantification of COVID-19 using chest CT scans. The main tasks of interest are the automatic segmentation of lung and lung lesions in chest CT scans of confirmed or suspected COVID-19 patients. In this study, we compare twelve deep learning algorithms using a multi-center dataset, including both open-source and in-house developed algorithms. Results show that ensembling different methods can boost the overall test set performance for lung segmentation, binary lesion segmentation and multiclass lesion segmentation, resulting in mean Dice scores of 0.982, 0.724 and 0.469, respectively. The resulting binary lesions were segmented with a mean absolute volume error of 91.3 ml. In general, the task of distinguishing different lesion types was more difficult, with a mean absolute volume difference of 152 ml and mean Dice scores of 0.369 and 0.523 for consolidation and ground glass opacity, respectively. All methods perform binary lesion segmentation with an average volume error that is better than visual assessment by human raters, suggesting these methods are mature enough for a large-scale evaluation for use in clinical practice.

Reference