Resolution impact on breast cancer diagnosis: individual micro-CT microcalcifications in focus
 
Resolution impact on breast cancer diagnosis: individual micro-CT microcalcifications in focus 
 
Redona Brahimetaj, Jan Cornelis, Chantal Van Ongeval, , Bart Jansen
 
Abstract 

Breast microcalcifications (MCs) are the main manifestation and/or robust marker of an early non-palpable breast cancer. However, they are not always restricted to malignancies as they are also present in common benign lesions. Traditionally, breast MCs are only analysed in clusters because regular in vivo mammography has limited resolution for conducting individual MC analysis. With our study, we markedly deviate from conventional methods/studies by: (a) focusing on individual breast MCs instead of clusters; (b) investigating the influence of image resolution on breast cancer diagnosis using radiomics features extracted from highresolution 3D micro-CT individual MC images.