Publication Details
Delphine Van Laethem, Frederik Van de Steen, Daphne Kos, Maarten Naeyaert, Peter Van Schuerbeek, Samar Hatem, Marc Schiltz, Miguel D'haeseleer, Marie D'hooghe, Jeroen Van Schependom, Nagels, Guy

Contribution To Conference


Background/Purpose: The management of cognitive impairment is an important goal in the treatment of multiple sclerosis (MS). While cognitive rehabilitation improves cognitive performance in MS, research in the elderly indicates a greater improvement of cognitive, physical and functional outcomes after combined cognitive-motor rehabilitation. Here we present the protocol of a randomised controlled clinical trial to assess whether combined cognitive-motor telerehabilitation is more effective in improving working memory than only cognitive or motor training. Methods: The CoMoTeMS-trial is a two-centre, randomised, controlled and blinded clinical trial. 90 MS patients will receive 90 minutes/week of either combined cognitive-motor or only cognitive or motor telerehabilitation for 12 weeks. The primary outcome is a change in the digit span backwards. Secondary outcomes are other cognitive changes, changes in Expanded Disability Status Scale, walking performance, fine motor skills, anxiety and depression, fatigue, quality of life, electroencephalography and brain MRI. Discussion: We hypothesise that the improvement in digit span backwards after 12 weeks of treatment will be significantly higher after combined cognitive-motor telerehabilitation, compared to after only cognitive and only motor training.