Publication Details
Delphine Van Laethem, Denissen, Stijn, Costers, Lars, Annabel Descamps, Johan Baijot, Ann Van Remoortel, Annick Van Merhaegen-Wieleman, Marie D'hooghe, Miguel D'haeseleer, Dirk Smeets, Diana Maria Sima, Jeroen Van Schependom, Nagels, Guy

Multiple Sclerosis Journal

Contribution To Journal


Background: The Nine-Hole Peg Test (9HPT) is the golden standard to measure manual dexterity in people with multiple sclerosis (MS). However, administration requires trained personnel and dedicated time during a clinical visit. Objectives: The objective of this study is to validate a smartphone-based test for remote manual dexterity assessment, the icompanion Finger Dexterity Test (FDT), to be included into the icompanion application. Methods: A total of 65 MS and 81 healthy subjects were tested, and 20 healthy subjects were retested 2 weeks later. Results: The FDT significantly correlated with the 9HPT (dominant: ? = 0.62, p < 0.001 non-dominant: ? = 0.52, p < 0.001). MS subjects had significantly higher FDT scores than healthy subjects (dominant: p = 0.015 non-dominant: p = 0.013), which was not the case for the 9HPT. A significant correlation with age (dominant: ? = 0.46, p < 0.001 non-dominant: ? = 0.40, p = 0.002), Expanded Disability Status Scale (EDSS, dominant: ? = 0.36, p = 0.005 non-dominant: ? = 0.31, p = 0.024), and disease duration for the non-dominant hand (? = 0.31, p = 0.016) was observed. There was a good test–retest reliability in healthy subjects (dominant: r = 0.69, p = 0.001 non-dominant: r = 0.87, p < 0.001). Conclusions: The icompanion FDT shows a moderate-to-good concurrent validity and test–retest reliability, differentiates between the MS subjects and healthy controls, and correlates with clinical parameters. This test can be implemented into routine MS care for remote follow-up of manual dexterity.

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